Introduction to Biological and Small Molecule Drug Research and Development: theory and case studies

Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs.\n\nThe book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the business and management issues of these approaches. The latter part of the book provides carefully selected real-life case studies illustrating how the theory presented in the first part of the book is actually put into practice. Studies include Herceptin/T-DM1, erythropoietin (Epogen/Eprex/Neo Recormon), anti-HIV protease inhibitor Darunavir, and more.Introduction to Biological and Small Molecule Drug Research and Development is intended for late-stage undergraduates or postgraduates studying chemistry (at the biology interface), biochemistry, medicine, pharmacy, medicine, or allied subjects. The book is also useful in a wide variety of science degree courses, in post-graduate taught material (Masters and Ph D), and as basic background reading for scientists in the pharmaceutical industry.For the first time, the fundamental scientific principles of biopharmaceuticals and small molecule chemotherapeutics are discussed side-by-side at a basic level Edited by three senior scientists with over 100 years of experience in drug research who have compiled the best scientific comparison of small molecule and biopharmaceuticals approaches to new drugs Illustrated with key examples of important drugs that exemplify the basic principles of pharmaceutical drug research and development Additional ISBNs9781299592032Introduction to Biological and Small Molecule Drug Research and Development: theory and case studies 1st Edition is written by Ganellin, C. Robin; Jefferis, Roy; Roberts, Stanley M. and published by Elsevier (S&T). ISBNs for Introduction to Biological and Small Molecule Drug Research and Development: theory and case studies are 9780123971760, 9780123977700, 0123977703 and the print ISBNs are 9780123971760, 0123971764. Additional ISBNs include 9781299592032.